Molecular Hydrogen and Heart Attacks
Hydrogen treatment was found to significantly reduce the area of damaged heart muscle. Scientists observed that the left ventricular function after heart attack was improved and the hydrogen resulted in a positive effect on the heart remodelling. The positive effects were explained by expression of antioxidant enzymes in the mitochondria.
Molecular Hydrogen and Stroke
In a clinical trial, 50 patients were divided into two groups. One group received a conventional medical therapy and the other received daily 3% hydrogen inhalations in addition to the conventional treatment.
Regular MRI studies showed significant reduction in infarct size and a faster normalisation of the tissue damaged by stroke in the hydrogen group.
Additionally, the hydrogen-treated patients showed significantly better results in terms of their mobility and their ability to perform activities of daily living.
Molecular Hydrogen and The Gut
The chronic inflammation that occurs during an inflammatory bowel disorder such as ulcerative colitis could be diminished by the administration of hydrogen. A study found that symptoms like diarrhea and weight loss were reduced. Furthermore, there was a general cytoprotective effect provided by hydrogen.
Molecular Hydrogen and Oxidative Stress Related Diseases
Oxidative stress plays a crucial role in diseases such as ischaemic heart disease, stroke, acute lung injury, and inflammatory bowel disease.
During an acute circulatory disorder, tissue damage often follows. Permanent structural damage and functional disorders are the results. The body is only able to repair this damage to a limited extent by itself, and the initial state before the original injury is usually not attainable.
Molecular Hydrogen and Brain/Nerve Diseases
Recent studies suggest that hydrogen may be able to successfully treat Parkinson’s disease, Alzheimer’s disease, ALS, traumatic nerve injuries and bipolar disorders. A recently published study has shown that hydrogen exhibits cell-protective effects in the central nervous system in diseases caused by oxidative stress.
The researchers have found an increase in glutathione synthesis caused by hydrogen-mediated gene expression
In one clinical trial on 48 patients with Parkinson’s disease, the study found that the group which had a hydrogen intake everyday for 48 weeks showed significantly improved symptoms compared to the control group which showed worsening symptoms. This includes rapid improvement of tremor in the hands and improved mood and anxiety.
Molecular Hydrogen and Asthma
Molecular Hydrogen is particularly favourable when considering respiratory medicine because underlying inflammation is known to drive the pathological progress of numerous respiratory conditions, including asthma, Long-COVID and chronic obstructive pulmonary disorder.
In one trial based on an asthmatic model, the scientists indicated that oxidative stress was an important mechanism in the pathogenesis of asthma.
As a result of the Molecular Hydrogen, inflammation was down-regulated which had observable improved effects on the pathophysiology.
Molecular Hydrogen and Pulmonary Diseases
- Reduced lung-resistance
- Reduced mucus formation
- Reduced inflammatory markers such as IL-4/13 and TNF-alpha
- Reduced inflammation of cells in the lungs
- Reduced oxidative stress markers in lung homogenates
- Reduced oxidative stress markers in lung homogenates